Enzalutamide: What It Is and How It Works

If you’ve been told to start enzalutamide, you’re probably dealing with prostate cancer that’s grown beyond the early stage. Enzalutamide is a pill that blocks androgen receptors – basically it stops testosterone from feeding cancer cells. By cutting off that signal, the drug slows tumor growth and can shrink tumors in many men.

The medicine comes as a 160 mg tablet you take once daily with or without food. It’s meant to be taken continuously unless your doctor says otherwise. Because it stays in your system for a while, you’ll feel its effects even if you miss a dose – but try not to make that a habit.

When Do Doctors Prescribe Enzalutamide?

Enzalutamide is usually recommended after other hormone therapies stop working. It’s also used before chemotherapy in some cases, especially when the cancer has spread to bones or lymph nodes. Your oncologist will look at your PSA levels (the blood test that tracks prostate activity) and imaging scans to decide if enzalutamide is right for you.

It’s not a cure, but it can give you more time with fewer symptoms. Many men stay on the drug for months or even years as long as they tolerate it well. Your doctor will schedule regular blood work to check liver function and hormone levels – those tests help catch problems early.

Managing Common Side Effects

The most frequent complaints are fatigue, hot flashes, and a mild headache. You might also notice joint aches or a drop in blood pressure when you stand up quickly. If any of these get annoying, try drinking more water, getting regular light exercise, and sleeping on a cooler pillow to tame the heat.

Serious side effects are rarer but worth watching for. A small number of users develop seizures, especially if they have a history of brain issues. Also keep an eye on any sudden mood changes or severe stomach pain – those could signal something more serious. If anything feels off, call your doctor right away.

Some men experience a drop in testosterone levels that leads to reduced libido or erectile dysfunction. Talk openly with your healthcare team; they might adjust the dose or suggest supportive meds.

Remember, you’re not alone. Many online forums and patient groups share practical tips – like using compression socks for leg swelling or setting reminders on your phone to take the pill at the same time each day.

Finally, never mix enzalutamide with strong CYP3A4 inhibitors (like certain antifungal creams) without checking first. Those interactions can raise drug levels and increase side‑effect risk.

Bottom line: enzalutamide can be a powerful tool against advanced prostate cancer when you follow the dosing schedule, keep up with lab checks, and stay alert to how your body reacts. Stay in touch with your doctor, report any new symptoms, and you’ll give yourself the best chance at a smoother treatment journey.